- URL: https://inflazome.estd.dev/
- Date: 09/06/24 10:00:24
Webpage Performance Test Result
- Settings: Desktop
v128
Cable
Frankfurt, GermanyMore
- Test runs: 1
- Connectivity: 5000/1000 Kbps, 28ms Latency
- Custom Metrics
View:
Requests Details
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Page Performance Metrics (Run 1)
View run details: Run 1 (Repeat View)
| TTFB | Start Render | FCP | Speed Index | LCP | CLS | TBT | DC Time | DC Requests | DC Bytes | Total Time | Total Requests | Page Weight |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Visual Page Loading Process (Explore)
| Navigation Timings | |
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| domContentLoadedEvent | loadEvent |
| 0.773s - 0.778s (0.005s) | 7.853s - 7.859s (0.006s) |
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- <html lang="en"><head> <meta charset="UTF-8"> <meta name="viewport" content="width=device-width, initial-scale=1.0, user-scalable=no"> <meta http-equiv="X-UA-Compatible" content="ie=edge"> <title>Inflazome | Home</title> <link rel="apple-touch-icon" sizes="180x180" href="/assets/icon/apple-touch-icon.png"> <link rel="icon" type="image/png" sizes="32x32" href="/assets/icon/favicon-32x32.png"> <link rel="icon" type="image/png" sizes="16x16" href="/assets/iconfavicon-16x16.png"> <!-- <link rel="manifest" href="/assets/icon/site.webmanifest"> --> <link rel="mask-icon" href="/assets/icon/safari-pinned-tab.svg" color="#5bbad5"> <meta name="msapplication-TileColor" content="#e1f2f1"> <meta name="theme-color" content="#ffffff"> <!-- Add SEO Snippet --> <title>Inflazome | Home</title> <meta name="keywords" content="Inflazome, NLRP3, Inflammasome, inflammation, Parkinsons’s, Alzheimer’s, Gout, Arthritis, Cardiovascular Disease, Luke O’Neill, Matt Cooper, interleukin, pyroptosis"> <meta name="description" content="We are dedicated to improving people’s lives by delivering new medicines that stop harmful inflammation."> <meta property="og:image" content=""> <meta property="og:url" content="https://inflazome.estd.dev"> <link href="https://inflazome.estd.dev/build/app.css" rel="stylesheet"> <!-- Add Scripts --> <script type="text/javascript" async="" src="https://www.google-analytics.com/analytics.js"></script><script async="" src="https://www.googletagmanager.com/gtm.js?id=GTM-TBNRWP3"></script><script src="https://inflazome.estd.dev/build/all.js"></script> <script src="https://inflazome.estd.dev/build/app.js"></script> <!-- Global site tag (gtag.js) - Google Analytics --> <script async="" src="https://www.googletagmanager.com/gtag/js?id=UA-149886773-1"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'UA-149886773-1'); </script> <!-- Google Tag Manager --> <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-TBNRWP3');</script> <!-- End Google Tag Manager --> </head> <body> <header class="header"> <nav class="header_nav"> <a href="/" class="header_logo"> <img src="/assets/images/inflazome-logo.svg" alt="Inflazome Logo"> </a> <ul class="u-desktop"> <li><a href="https://inflazome.estd.dev/about-us">About Us</a></li> <li><a href="https://inflazome.estd.dev/science">Science</a></li> <li><a href="https://inflazome.estd.dev/pipeline">Pipeline</a></li> <li><a href="https://inflazome.estd.dev/news">News</a></li> </ul> </nav> <a href="#" class="header_burger"> <span></span> <span></span> <span></span> </a> </header> <div class="cookie"> <p class="cookie_message">This website uses cookies to ensure you get the best experience on our website. <a href="/data-protection">More info</a></p> <button class="btn">Got It!</button> </div> <div class="flyout"> <ul class="flyout_menu"> <!-- <li class="u-mobile"> --> <li> <a href="https://inflazome.estd.dev/about-us">About Us</a> </li> <!-- <li class="u-mobile"> --> <li> <a href="https://inflazome.estd.dev/science">Science</a> </li> <!-- <li class="u-mobile"> --> <li> <a href="https://inflazome.estd.dev/pipeline">Pipeline</a> </li> <!-- <li class="u-mobile"> --> <li> <a href="https://inflazome.estd.dev/news">News</a> </li> <li><a href="https://inflazome.estd.dev/diseases">Diseases</a></li> <li><a href="https://inflazome.estd.dev/partnerships">Partnerships</a></li> <li><a href="https://inflazome.estd.dev/publications">Publications</a></li> <li><a href="https://inflazome.estd.dev/contact">Contact</a></li> <li><a href="https://inflazome.estd.dev/data-protection">Data Protection</a></li> </ul> <ul class="flyout_social"> <li> <a target="_blank" href="https://www.linkedin.com/company/inflazome-ltd" alt="LinkedIn Link"> <img src="https://inflazome.estd.dev/media/pages/media/1055789561-1675194402/linkedin.svg" alt="LinkedIn"> </a> </li> <li> <a target="_blank" href="https://twitter.com/inflazome" alt="Twitter Link"> <img src="https://inflazome.estd.dev/media/pages/media/2530630424-1675194402/twitter.svg" alt="Twitter"> </a> </li> <li> <a target="_blank" href="mailto:[email protected]" alt="Email Link"> <img src="https://inflazome.estd.dev/media/pages/media/1493353007-1675194402/email.svg" alt="Email"> </a> </li> </ul> </div> <main class="home"> <div class="slider flickity-enabled is-draggable" tabindex="0"> <div class=""> </div> <div class="flickity-viewport" style="height: 850.625px; touch-action: pan-y;"><div class="flickity-slider" style="left: 0px; transform: translate3d(-299.82%, 0px, 0px);"><div class="slide" style="position: absolute; left: 0%;" aria-hidden="true"><img src="media/home_slider_c.jpg" alt=""> <h2>Targeted therapies for inflammatory diseases</h2></div><div class="slide" style="position: absolute; left: 100%;" aria-hidden="true"><img src="media/home_heroslider_5.jpg" alt=""> <h2>Improving lives with focused research</h2></div><div class="slide" style="position: absolute; left: 200%;" aria-hidden="true"><img src="media/home_slider_a.jpg" alt=""> <h2>Inflammasomes are a root cause of inflammation</h2></div><div class="slide is-selected" style="position: absolute; left: 300%;"><img src="media/home_slider_b.jpg" alt=""> <h2>Inflammation leads to many of our most debilitating diseases</h2></div></div></div><ol class="flickity-page-dots"><li class="dot" aria-label="Page dot 1"></li><li class="dot" aria-label="Page dot 2"></li><li class="dot" aria-label="Page dot 3"></li><li class="dot is-selected" aria-label="Page dot 4" aria-current="step"></li></ol></div> <div class="narrow anim center visible"> <div class=""> <h3>At Inflazome, we are dedicated to improving people’s lives by delivering new medicines that stop inflammation. Our founders are globally acknowledged scientific leaders whose vision is to transition their work from the lab to life.</h3> </div> </div> <div class="anim grid-12"> <div class=""> <h3>Focused Research Today. <br>Better Results Tomorrow.</h3> </div> <div class=""> <p>Our mission at Inflazome is to identify and develop potent, best-in-class, small molecule NLRP3 modulators as treatments for a broad range of inflammatory diseases.</p> <p><a class="btn " href="/science">Discover the Science</a></p> </div> </div> <div class="anim grid-12"> <div class=""> <h3>The Challange of Targeting Inflammation</h3> <figure class="bottom"><img alt="" src="https://inflazome.estd.dev/media/pages/media/176276387-1675194402/challenge-lab.jpg"></figure> </div> <div class=""> <p>When immune cells recognise an infection or harmful substances in the body that needs to be neutralised, inflammasomes – protein complexes in these immune cells – generate signals that cause inflammation and recruit other cells to help. This short term, beneficial inflammation allows the cells to fight and clear the infection or foreign particles, restoring us to good health.</p> <p>However, unwanted inflammation can happen if immune cells are activated out of control. Inflammasomes generate signals calling for reinforcements whenever immune cells are stimulated. Sometimes the cells are over-stimulated, and in this case, the resulting overactive inflammatory response can damage healthy tissue, which in turn causes more inflammasomes to trigger, creating more inflammation.</p> <p>Our mission is to stop this cycle of harmful inflammation and the development of associated diseases. The NLRP3 inflammasome has been identified as a key driver of this process, and has been implicated in a large number of diseases. At Inflazome we are identifying and developing potent, best-in-class, small molecule NLRP3 inhibitors to stop inflammation before it gets out of control.</p> </div> </div> <div class="white"> <div class="heading anim center"> <h2>The Impact of Inflammation</h2> </div> <div class=" grid-3 center"> <div class="anim"> <h1>3 <small>Million</small></h1> <p>The number of US adults reported being diagnosed with Inflammatory Bowel Disease (either Crohn’s disease or ulcerative colitis) or 1.3% of the adult population.</p> </div> <div class="anim"> <h1>8 <small>Million</small></h1> <p>People living with Parkinson’s disease worldwide.</p> </div> <div class="anim"> <h1>10%</h1> <p>In 2015-2016, approximately 8% of the US adult population reported some form of Cardiovascular Disease (including coronary heart disease, angina, previous myocardial infarction or stroke).</p> </div> </div> </div> <div class="anim"> <div class=" center"> <h2>Our Pursuits</h2> </div> <div class="nopad grid-2 white"> <div class="nopad"> <figure class="cover"><img alt="" src="https://inflazome.estd.dev/media/pages/media/140778187-1675194402/lab.jpg"></figure> </div> <div class="tile pt"> <ol> <li> <p><strong>Leadership Strength</strong><br> We have a dedicated and highly experienced management team committed to developing therapeutics with a high impact for patients.</p> </li> <li> <p><strong>World-Class Research</strong><br> Our research has lead us to develop a pipeline of best-in-class inhibitors of the NLRP3 inflammasome to treat inflammatory diseases.</p> </li> <li> <p><strong>Pioneering Development</strong><br> We are focused on developing proprietary, industry-leading, orally available drugs that block activation of the NLRP3 inflammasome in order to address unmet medical needs in inflammatory diseases.</p> </li> </ol> </div> </div> </div> <div class=""> <div class="narrow center"> <h2>The Pipeline</h2> <p>Inflazome is a true platform company underpinned by a robust pipeline of potent and proprietary small molecule NLRP3 inhibitors.</p> </div> <div class="pipeline "> <nav> <ol> <li>Lead Optimization</li> <li>Pre-clinical</li> <li>Phase I</li> <li>Phase II</li> </ol> </nav> <div class="molecule anim"> <div class="molecule_bar"> <span></span><span></span><span></span> <span style="width:70%"></span> <h5>Inzomelid</h5> </div> <div class="molecule_info"><div class="molecule_description"><p>Inzomelid is a potent, selective, brain-penetrant NLRP3 inhibitor that is currently in Phase I trials.</p></div><div class="molecule_areas"><strong>Potential Disease Areas</strong><ul> <li>Orphan Diseases</li> <li>CNS Diseases</li> </ul></div></div> </div> <div class="molecule anim"> <div class="molecule_bar"> <span></span><span></span><span></span> <span style="width:62.5%"></span> <h5>Somalix</h5> </div> <div class="molecule_info"><div class="molecule_description"><p>Somalix is a potent, selective, peripherally restricted NLRP3 inhibitor that is currently in Phase I trials.</p></div><div class="molecule_areas"><strong>Potential Disease Areas</strong><ul> <li>Rheumatic Diseases</li> <li>Cardiovascular Disease</li> </ul></div></div> </div> <div class="molecule anim"> <div class="molecule_bar"> <span></span><span></span><span></span> <span style="width:40%"></span> <h5>3rd Candidate</h5> </div> <div class="molecule_info"><div class="molecule_description"><p>Our 3rd candidate is a potent, selective, peripherally restricted NLRP3 inhibitor.</p></div><div class="molecule_areas"><strong>Potential Disease Areas</strong><ul> <li>Rheumatic Diseases</li> <li>Cardiovascular Disease</li> </ul></div></div> </div> </div> </div> <div class="grid-12"> <div class="anim "> <h2>Our Medicines</h2> <p>Since Inflazome was founded in 2016, we have invested heavily in our Medicinal Chemistry activities and Intellectual Property filings. We now have two clinical-stage therapeutic candidates - one brain penetrant and one peripherally restricted - that we expect to address unmet medical needs in multiple disease areas. Looking ahead, we plan to advance additional gut-restricted and topical molecules to cover additional diseases where NLRP3 activation is a key driver.</p> <p><a class="btn " href="/pipeline">See the Pipeline</a></p> </div> <div class=""> <div class="tile anim grid-13 white"> <div><strong>Inzomelid</strong></div><div><p>A potent, selective NLRP3 inhibitor with brain penetrating properties.</p></div></div> <div class="tile anim grid-13 white"> <div><strong>Somalix</strong></div><div><p>A potent, selective, peripherally restricted NLRP3 inhibitor.</p></div></div> <div class="tile anim grid-13 white"> <div><strong>3rd Candidate</strong></div><div><p>A potent, selective, peripherally restricted NLRP3 inhibitor.</p></div></div> <div class="tile anim grid-13 white"> <div><strong>Research</strong></div><div><p>Inflazome is exploring tissue-specific inhibitors for Gastro-Intestinal (IBD, Crohn’s) and Dermatological (Psoriasis, Atopic Dermatitis) diseases.</p></div></div> </div> </div> <div class="quote"> <div class=""> <div class="quote_text anim"><h4>We always strive to move scientific discoveries as quickly as possible from the lab to the clinic. We are committed to making a significant difference to patient’s lives.</h4><div class="quote_credit"><strong>Dr Matthew Cooper</strong><br>Co-founder & Chief Executive Officer</div></div> <figure class="quote_image anim"><img alt="" src="https://inflazome.estd.dev/media/pages/media/1003058223-1675194402/profile.jpg"></figure> </div> </div> <div class="narrow anim center"> <div class=""> <h2>Our Partnerships</h2> <p>Inflazome has partnered with the Michael J. Fox Foundation for Parkinson’s Research, who provided funding in excess of US$1 million to support the development of a brain imaging probe. This will be used to support clinical trials to treat neurodegenerative diseases.</p> <p>We are open to partnering with Biotech and Pharma companies with excellent clinical development capabilities.</p> <p><a class="btn " href="/partnerships">Our Partnerships</a></p> </div> </div> <div class="quote"> <div class=""> <figure class="quote_image anim"><a href="https://www.michaeljfox.org/" rel="noopener noreferrer" target="_blank"><img alt="" src="https://inflazome.estd.dev/media/pages/media/1726118387-1675194402/home_jamieeberling.png"></a></figure> <div class="quote_text anim"><h4>An imaging tool to visualise neuroinflammation may help investigate Parkinson’s onset and progression as well as evaluate new treatments that could alter the course of the disease. Our Foundation is investing in this research due to the significant potential impact on drug development and patient lives.</h4><div class="quote_credit"><strong>Dr Jamie Eberling</strong><br>Director of Research Programs<br>Michael J. Fox Foundation for Parkinson’s Research</div></div> </div> </div> <div class="page anim"> <div class=" center"> <h3>Follow our Progress & Insights</h3> <p>Inflazome is making rapid progress in advancing our clinical and preclinical assets. Keep up with the latest news on Inflazome’s research and development activities with regular email updates.</p> <form id="form" class="mailchimp" method="POST" action="/subscribe"><input name="email" type="email"><input type="submit" value="Sign Up"></form> </div> </div> </main> <section class="cta black center anim"> <div class="center"> <h2>Speak to us about<br>a better tomorrow</h2> <p><a class="btn" href="/contact">Contact Us</a></p> </div> </section> <div class="overlay hide"> <a href="#" class="overlay_close">×</a> <div class="overlay_content"> </div> </div> <footer class="footer"> <ul class="footer_left anim"> <li><a href="https://inflazome.estd.dev/data-protection">Data Protection</a></li> </ul> <ul class="footer_middle anim"> <li><a href="https://inflazome.estd.dev/about-us">About Us</a></li> <li><a href="https://inflazome.estd.dev/science">Science</a></li> <li><a href="https://inflazome.estd.dev/pipeline">Pipeline</a></li> <li><a href="https://inflazome.estd.dev/news">News</a></li> </ul> <ul class="footer_right anim"> <li><a href="https://inflazome.estd.dev/partnerships">Partnerships</a></li> <li><a href="https://inflazome.estd.dev/publications">Publications</a></li> <li><a href="https://inflazome.estd.dev/contact">Contact</a></li> </ul> </footer> <div class="grad"> <span></span> </div> </body></html>
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