Can webpagetest only be used for synthetic testing ?

[webuser]

I understand that webpagetest can be used to simulate user behaviour and measure the metrics of the website while doing so.

Can it be used to understand performance with real users ? For example, if there is an issue with the perf of the website at a particular client location, how can I best use webpagetest to debug the issue ?

Thanks! Sorry, if the question sounds vague. I can add more details.